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KMID : 0604520130390010039
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Journal of the Society of Cosmetic Scientists of Korea
2013 Volume.39 No. 1 p.39 ~ p.46
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The Protective Effect of Mineral Water Against UVB Irradiation
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Lee Sung-Hoon
Min Dae-jin
Na Yong-Joo
Shim Jong-Won
Kwon Lee-Kyoung
Cho Jun-Cheol
Lee Hae-Kwang
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Abstract
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Bicationic minerals such as calcium and magnesium are known to protect the skin barrier. The principal objective of this study was to evaluate the skin barrier protective effects of mineral water, which is composed of calcium, magnesium, manganese, and fluorine. UVB irradiation induces a destruction of tight junction (TJ) components. The TJ permeability barrier was also disrupted by UVB irradiation. We employed a skin equivalent model to assess the efficacy of mineral water in this regard. Mineral water maintained the structure of the skin equivalents following UVB irradiation. The results of the TJ permeability assay showed that mineral water helped to maintain the TJ permeability barrier after UVB irradiation in skin equivalent model. Mineral water supported the structure of TJ components and restored the occludin protein level in differentiated normal human keratinocytes after UVB irradiation. In conclusion, we found out the protective effect of mineral water against UVB irradiation.
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KEYWORD
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mineral water, skin barrier, tight junction, skin equivalent, UVB irradiation
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